A kinetic study of methanol to olefins (MTO) process has been carried out for industrial DMTO catalyst in a Φ19×350mm fluidized bed reactor. The industrial DMTO catalyst is an improved SAPO-34 catalyst. The temperature of the experiments is in the range of 573K to 763K. A lumped kinetic model, including catalyst deactivation, is proposed based on the hydrocarbon pool mechanism. The lumped kinetic model, incorporated with a simple dynamic fluidized bed two-phase model, can predict the experimental data well.